KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MARK1
All Species:
36.36
Human Site:
Y732
Identified Species:
66.67
UniProt:
Q9P0L2
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P0L2
NP_061120.3
795
89003
Y732
L
D
A
N
N
C
D
Y
E
Q
K
E
R
F
L
Chimpanzee
Pan troglodytes
XP_001172839
796
89049
Y733
L
D
A
N
N
C
D
Y
E
Q
K
E
R
F
L
Rhesus Macaque
Macaca mulatta
XP_001115611
778
86745
S715
L
D
A
N
S
C
Q
S
E
L
H
E
K
Y
M
Dog
Lupus familis
XP_536123
782
87409
Y719
L
D
A
N
N
C
D
Y
E
Q
K
E
R
F
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8VHJ5
795
88528
Y732
L
D
A
N
T
C
D
Y
E
Q
K
E
R
F
L
Rat
Rattus norvegicus
O08678
793
88216
Y730
L
D
A
N
T
C
D
Y
E
Q
R
E
R
F
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511751
793
88836
Y730
L
D
A
N
N
C
D
Y
E
Q
K
E
R
F
L
Chicken
Gallus gallus
Q9IA88
798
88848
L702
K
A
S
N
S
L
L
L
S
E
L
Q
R
E
N
Frog
Xenopus laevis
NP_001085126
792
88624
Y729
L
D
A
N
N
C
D
Y
E
Q
K
E
R
F
L
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
Y1075
M
E
S
D
H
N
G
Y
G
S
R
S
T
Q
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9TW45
1192
126331
Y1129
L
D
A
N
G
C
D
Y
E
Q
R
E
R
Y
M
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92958
512
58671
E454
N
Q
L
H
F
R
D
E
S
S
I
I
E
D
D
Baker's Yeast
Sacchar. cerevisiae
P06782
633
72027
I575
M
V
I
Q
L
F
Q
I
E
T
N
N
Y
L
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
68.9
95.9
N.A.
94.9
94.3
N.A.
92.8
30.4
88.6
27.8
N.A.
N.A.
N.A.
40.7
N.A.
Protein Similarity:
100
99.3
80.2
96.8
N.A.
97.3
96.9
N.A.
95.9
51.3
94.2
44
N.A.
N.A.
N.A.
51
N.A.
P-Site Identity:
100
100
46.6
100
N.A.
93.3
86.6
N.A.
100
13.3
100
6.6
N.A.
N.A.
N.A.
73.3
N.A.
P-Site Similarity:
100
100
73.3
100
N.A.
93.3
93.3
N.A.
100
40
100
46.6
N.A.
N.A.
N.A.
93.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.9
28
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
44.4
46.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
70
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
70
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
70
0
8
0
0
70
0
0
0
0
0
0
8
8
% D
% Glu:
0
8
0
0
0
0
0
8
77
8
0
70
8
8
0
% E
% Phe:
0
0
0
0
8
8
0
0
0
0
0
0
0
54
0
% F
% Gly:
0
0
0
0
8
0
8
0
8
0
0
0
0
0
0
% G
% His:
0
0
0
8
8
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
8
0
0
8
8
0
0
0
% I
% Lys:
8
0
0
0
0
0
0
0
0
0
47
0
8
0
0
% K
% Leu:
70
0
8
0
8
8
8
8
0
8
8
0
0
8
54
% L
% Met:
16
0
0
0
0
0
0
0
0
0
0
0
0
0
16
% M
% Asn:
8
0
0
77
39
8
0
0
0
0
8
8
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
8
0
0
16
0
0
62
0
8
0
8
0
% Q
% Arg:
0
0
0
0
0
8
0
0
0
0
24
0
70
0
0
% R
% Ser:
0
0
16
0
16
0
0
8
16
16
0
8
0
0
8
% S
% Thr:
0
0
0
0
16
0
0
0
0
8
0
0
8
0
0
% T
% Val:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
70
0
0
0
0
8
16
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _